Crude Polysaccharides Extracted From Several Medicinal Fungi
Exhibit Hypoglycemic Functions in Mice
Abstract:The hypoglycemic effects of crude polysaccharides extracted from fivemedicinal fungi were evaluated using alloxan-induced diabetic mice.High(1 g/kg)and low(0.5 g/kg) doses of polysaccharides extracted from Cordyceps taii and C.memorabilis caused significant (P0.01) decreases in mice blood sugar levels.Polysaccharides from Ganoderma lucidum and C.militaris fruit bodies both exhibitedweak hypoglycemic effects at significance levels of P0.01 and P0.05 for high andlow doses,respectively. Polysaccharide extracted from mycelium of a Phellinus sp.was significantly(P0.05)hypoglycemic at higher dose levels but lower doses hadno effect.
Key wo rds:Cordyceps;P he llinus Ganoderma po lysaccharides;hypo glycemiceffect
Medicinal fungi are a very important part of traditional Chinese herbal medicine.Extensive research on the structure and bioactivity of fungal components hasindicated that fungal polysaccharides in particular are highly effective in maintaininggeneral good health, and in the treatment of certain diseases such as hyperglycemia.For example, polysaccharides extracted from Ganoderma lucidum,Cordyceps spp,Coriulus versicolor, Auricularia polytricha,A. auricula, Tremella fuciformis, T.aurantialba, Hericium erinaceum, Grifola frondosa, Armillariella mellea andAgrocybe praecox increased the rate of insulin secretion and lowered blood glucoselevels 1,2 .We now report hypoglycemic functions associated with crudepolysaccharide preparations from fruit bodies o f G. lucidum and Cordycep s militaris,and from vegetative mycelia of Cordyceps taii,Cordyceps memorabilis and Phellinussp.
1 Materials and Methods
1.1Strains and test sample
All fungal strains were provided by the Guangdong Institute of Microbiology(GIM).Phellinus sp.GIMYY0512 was isolated from a fruit body collected from thewild at Preah Vihear,Cambodia, and was identified as a new species of Phellinusthrough ITS sequence analysis (ITS sequence deposited in Genbank under accessionNo. EU826013); Cordyceps taii GIMYY0508 and Cordyceps memorabilisGIMYY0607 were isolated from fruit bodies collected from the wild at Henyang,Hunan Province and Dinghu, Guangdong Province, respectively. Fruit bodies ofGanoderma lucidum GIMYY0403 and Cordyceps militaris GIMYY0610 werecultivated in o ur labo rato ry.
青果云香港CN2_GIA主机测评青果云香港多线BGP网络,接入电信CN2 GIA等优质链路,测试IP:45.251.136.1青果网络QG.NET是一家高效多云管理服务商,拥有工信部颁发的全网云计算/CDN/IDC/ISP/IP-VPN等多项资质,是CNNIC/APNIC联盟的成员之一。青果云香港CN2_GIA主机性能分享下面和大家分享下。官方网站:点击进入CPU内存系统盘数据盘宽带ip价格购买地...
10gbiz怎么样?10gbiz 美国万兆带宽供应商,主打美国直连大带宽,真实硬防。除美国外还提供线路非常优质的香港、日本等数据中心可供选择,全部机房均支持增加独立硬防。洛杉矶特色线路去程三网直连(电信、联通、移动)回程CN2 GIA优化,全天低延迟。中国大陆访问质量优秀,最多可增加至600G硬防。香港七星级网络,去程回程均为电信CN2 GIA+联通+移动,大陆访问相较其他香港GIA线路平均速度更...
传统农历新年将至,国人主机商DogYun(狗云)发来了虎年春节优惠活动,1月31日-2月6日活动期间使用优惠码新开动态云7折,经典云8折,新开独立服务器可立减100元/月;使用优惠码新开香港独立服务器优惠100元,并次月免费;活动期间单笔充值每满100元赠送10元,还可以参与幸运大转盘每日抽取5折码,流量,余额等奖品;商家限量推出一款年付特价套餐,共100台,每个用户限1台,香港VPS年付199元...