cellularBioactive Components of Cordyceps taii and Their Immune Functions in Mice

disable_functions  时间:2021-03-22  阅读:()

Bioactive Components of Cordyceps taii and Their Immune

Functions in Mice

Abstract:The polysaccharide,adenosine and mannitol components of Cordycepstaii collected from the wild were determined, and the effects of aqueous C. taiiextracts on immune functions in mice were investigated using carbon clearance anddelayed type hypersensitivity testing(DTH),and by determining thymic and splenicindices. Polysaccharide, adenosine and mannitol levels in C. taii were 36.20 mg/g,

0.27 mg/g and 80.20 mg/g, respectively.Aqueous C. taii extracts partially alleviatedthe suppressive effects on the thymic and splenic indices caused bycyclophosphamide, and increased nonspecific immunity and cellular immunefunctions.Toxicity tests revealed that the LD50 for aqueous C. taii extract on oraladministration was69.42 g/kg.

Key words:Cordyceps taii;polysaccharide;adenosine;mannitol;carbonclearance;cellular immune function

Cordyceps sinensis (Berk.) Sacc. is a rare medicinal fungus in China withnumerous special pharmacological effects favoured by consumers. However, C.sinensis yields are decreasing year by year and the price of this limited resource isnow very high due to over gathering.However, other species within the genusCordyceps have often been reported to have similar chemical composition andpharmacological effects1 and might, there fore, serve as efficient sub stitutes for C.sinensis.One such alternative species is C. taii Liang et Liu which was firstlydiscovered and reported in Guizhou Province in 1991 2 and has subsequently beenfound in Anhui, Henan, Hunan and Guangdong Provinces. Comparison of thechemical composition of C. sinensis and C. taii showed that both species had similaramino ac id,vitamin and microe lement components3 .The microelement and aminoacid composition ofC. taii mycelia have also been reported 4,5 ,and extracts ofC.taii mycelia have antiseptic 6 , immunoregulatory 6~9 and tumor cell growthinhibiting functions 10 . In order to provide a basis for utilizing C. taii as analternative forC. sinensis, we have compared the levels of various bioactivecomponents in these two species,and studied the effect of aqueous C. taii extracts onnon specific immune functions, thymic and splenic indices,and cellular immunity inmic e.

1 Materials and Methods

1.1 Materials

C. taii was supplied by Guangdong Jin Cordyceps Biological Development Co.Ltd,and C. s inens is wa s purchas ed from Guangzhou Tongrentang Drugstore.

博鳌云¥799/月,香港110Mbps(含10M CN2)大带宽独立服务器/E3/8G内存/240G/500G SSD或1T HDD

博鳌云是一家以海外互联网基础业务为主的高新技术企业,运营全球高品质数据中心业务。自2008年开始为用户提供服务,距今11年,在国人商家中来说非常老牌。致力于为中国用户提供域名注册(国外接口)、免费虚拟主机、香港虚拟主机、VPS云主机和香港、台湾、马来西亚等地服务器租用服务,各类网络应用解決方案等领域的专业网络数据服务。商家支持支付宝、微信、银行转账等付款方式。目前香港有一款特价独立服务器正在促销,...

特网云(1050元),IP数5 个可用 IP (/29) ,美国高防御服务器 无视攻击

特网云特网云为您提供高速、稳定、安全、弹性的云计算服务计算、存储、监控、安全,完善的云产品满足您的一切所需,深耕云计算领域10余年;我们拥有前沿的核心技术,始终致力于为政府机构、企业组织和个人开发者提供稳定、安全、可靠、高性价比的云计算产品与服务。官方网站:https://www.56dr.com/ 10年老品牌 值得信赖 有需要的请联系======================特网云美国高防御...

pacificrack:2021年七夕VPS特别促销,$13.14/年,2G内存/2核/60gSSD/1T流量,支持Windows

pacificrack官方在搞2021年七夕促销,两款便宜vps给的配置都是挺不错的,依旧是接入1Gbps带宽,KVM虚拟、纯SSD raid10阵列,支持包括Linux、Windows 7、10、server2003、2008、2012、2016、2019在内多种操作系统。本次促销的VPS请特别注意限制条件,见本文末尾!官方网站:https://pacificrack.com支持PayPal、支...

disable_functions为你推荐
accessdenied网页打开显示Access Denied,怎么解决开启javascript怎样打开JavaScript?360公司迁至天津天津360公司?360开户哪家好?360开户费多少?360推广怎么样?360效果怎么样?360和百度相比哪个更合适?生药http小型汽车网上自主编号申请机动车自主选号有几种办法discuz伪静态DZ怎么开启全站伪静态什么是seo学习SEO的好处是什么?zencart模板zen cart套用模板后,外观控制显示红色打不开,为什么?建站无忧求好点的免费建站网论坛版块图标请问论坛版块图标后面如何展示分类信息而不是显示主题和发表时间。求详细教程。
大庆服务器租用 韩国vps俄罗斯美女 iisphpmysql shopex空间 大容量存储 华为网络硬盘 怎么测试下载速度 支付宝扫码领红包 安徽双线服务器 网站加速软件 starry 中国电信网络测速 我的世界服务器ip 监控服务器 免费蓝钻 镇江高防 中国联通宽带测试 网络速度 云销售系统 脚本大全 更多