Bioactive Components of Cordyceps taii and Their Immune
Functions in Mice
Abstract:The polysaccharide,adenosine and mannitol components of Cordycepstaii collected from the wild were determined, and the effects of aqueous C. taiiextracts on immune functions in mice were investigated using carbon clearance anddelayed type hypersensitivity testing(DTH),and by determining thymic and splenicindices. Polysaccharide, adenosine and mannitol levels in C. taii were 36.20 mg/g,
0.27 mg/g and 80.20 mg/g, respectively.Aqueous C. taii extracts partially alleviatedthe suppressive effects on the thymic and splenic indices caused bycyclophosphamide, and increased nonspecific immunity and cellular immunefunctions.Toxicity tests revealed that the LD50 for aqueous C. taii extract on oraladministration was69.42 g/kg.
Key words:Cordyceps taii;polysaccharide;adenosine;mannitol;carbonclearance;cellular immune function
Cordyceps sinensis (Berk.) Sacc. is a rare medicinal fungus in China withnumerous special pharmacological effects favoured by consumers. However, C.sinensis yields are decreasing year by year and the price of this limited resource isnow very high due to over gathering.However, other species within the genusCordyceps have often been reported to have similar chemical composition andpharmacological effects1 and might, there fore, serve as efficient sub stitutes for C.sinensis.One such alternative species is C. taii Liang et Liu which was firstlydiscovered and reported in Guizhou Province in 1991 2 and has subsequently beenfound in Anhui, Henan, Hunan and Guangdong Provinces. Comparison of thechemical composition of C. sinensis and C. taii showed that both species had similaramino ac id,vitamin and microe lement components3 .The microelement and aminoacid composition ofC. taii mycelia have also been reported 4,5 ,and extracts ofC.taii mycelia have antiseptic 6 , immunoregulatory 6~9 and tumor cell growthinhibiting functions 10 . In order to provide a basis for utilizing C. taii as analternative forC. sinensis, we have compared the levels of various bioactivecomponents in these two species,and studied the effect of aqueous C. taii extracts onnon specific immune functions, thymic and splenic indices,and cellular immunity inmic e.
1 Materials and Methods
1.1 Materials
C. taii was supplied by Guangdong Jin Cordyceps Biological Development Co.Ltd,and C. s inens is wa s purchas ed from Guangzhou Tongrentang Drugstore.
月神科技怎么样?月神科技是由江西月神科技有限公司运营的一家自营云产品的IDC服务商,提供香港安畅、香港沙田、美国CERA、华中电信等机房资源,月神科技有自己的用户群和拥有创宇认证,并且也有电商企业将业务架设在月神科技的平台上。目前,香港CN2云服务器、洛杉矶CN2云主机、华中电信高防vps,月付20元起。点击进入:月神科技官方网站地址月神科技vps优惠信息:香港安畅CN2-GIA低至20元核心:2...
RackNerd 商家从2019年上线以来争议也是比较大的,一直低价促销很多网友都认为坚持时间不长可能会跑路。不过,目前看到RackNerd还是在坚持且这次黑五活动也有发布,且活动促销也是比较多的,不过对于我们用户来说选择这些低价服务商尽量的不要将长远项目放在上面,低价年付套餐服务商一般都是用来临时业务的。RackNerd商家这次发布黑五促销活动,一共有五款年付套餐,涉及到多个机房。最低年付的套餐...
目前,我们都在用哪个FTP软件?喜欢用的是WinSCP,是一款免费的FTP/SFTP软件。今天在帮助一个网友远程解决问题的时候看到他用的是FlashFXP FTP工具,这个工具以前我也用过,不过正版是需要付费的,但是网上有很多的绿色版本和破解版本。考虑到安全的问题,个人不建议选择破解版。但是这款软件还是比较好用的。今天主要是遇到他的虚拟主机无法通过FTP连接主机,这里我就帮忙看看到底是什么问题。一...