Bioactive Components of Cordyceps taii and Their Immune
Functions in Mice
Abstract:The polysaccharide,adenosine and mannitol components of Cordycepstaii collected from the wild were determined, and the effects of aqueous C. taiiextracts on immune functions in mice were investigated using carbon clearance anddelayed type hypersensitivity testing(DTH),and by determining thymic and splenicindices. Polysaccharide, adenosine and mannitol levels in C. taii were 36.20 mg/g,
0.27 mg/g and 80.20 mg/g, respectively.Aqueous C. taii extracts partially alleviatedthe suppressive effects on the thymic and splenic indices caused bycyclophosphamide, and increased nonspecific immunity and cellular immunefunctions.Toxicity tests revealed that the LD50 for aqueous C. taii extract on oraladministration was69.42 g/kg.
Key words:Cordyceps taii;polysaccharide;adenosine;mannitol;carbonclearance;cellular immune function
Cordyceps sinensis (Berk.) Sacc. is a rare medicinal fungus in China withnumerous special pharmacological effects favoured by consumers. However, C.sinensis yields are decreasing year by year and the price of this limited resource isnow very high due to over gathering.However, other species within the genusCordyceps have often been reported to have similar chemical composition andpharmacological effects1 and might, there fore, serve as efficient sub stitutes for C.sinensis.One such alternative species is C. taii Liang et Liu which was firstlydiscovered and reported in Guizhou Province in 1991 2 and has subsequently beenfound in Anhui, Henan, Hunan and Guangdong Provinces. Comparison of thechemical composition of C. sinensis and C. taii showed that both species had similaramino ac id,vitamin and microe lement components3 .The microelement and aminoacid composition ofC. taii mycelia have also been reported 4,5 ,and extracts ofC.taii mycelia have antiseptic 6 , immunoregulatory 6~9 and tumor cell growthinhibiting functions 10 . In order to provide a basis for utilizing C. taii as analternative forC. sinensis, we have compared the levels of various bioactivecomponents in these two species,and studied the effect of aqueous C. taii extracts onnon specific immune functions, thymic and splenic indices,and cellular immunity inmic e.
1 Materials and Methods
1.1 Materials
C. taii was supplied by Guangdong Jin Cordyceps Biological Development Co.Ltd,and C. s inens is wa s purchas ed from Guangzhou Tongrentang Drugstore.
云步云怎么样?云步云是创建于2021年的品牌,主要从事出售香港vps、美国VPS、日本VPS、香港独立服务器、香港站群服务器等,机房有香港、美国、日本东京等机房,目前在售VPS线路有CN2+BGP、CN2 GIA,香港的线路也是CN2直连大陆,该公司旗下产品均采用KVM虚拟化架构。目前,云步云提供香港安畅、沙田、大浦、葵湾、将军澳、新世界等CN2机房云服务器,2核2G5M仅72.5元/月起。点击进...
LOCVPS发来了新的洛杉矶CN2线路主机上线通知,基于KVM架构,目前可与香港云地、香港邦联机房XEN架构主机一起适用7折优惠码,优惠后最低美国洛杉矶CN2线路KVM架构2GB内存套餐月付38.5元起。LOCPVS是一家成立较早的国人VPS服务商,目前提供洛杉矶MC、洛杉矶C3、和香港邦联、香港沙田电信、香港大埔、日本东京、日本大阪、新加坡、德国和荷兰等机房VPS主机,基于KVM或者XEN架构。...
Sharktech 鲨鱼机房商家我们是不是算比较熟悉的,因为有很多的服务商渠道的高防服务器都是拿他们家的机器然后部署高防VPS主机的,不过这几年Sharktech商家有自己直接销售云服务器产品,比如看到有新增公有云主机有促销活动,一般有人可能买回去自己搭建虚拟主机拆分销售的,有的也是自用的。有看到不少网友在分享到鲨鱼机房商家促销活动期间,有赠送开通公有云主机$50,可以购买最低配置的,$49/月的...