Bioactive Components of Cordyceps taii and Their Immune
Functions in Mice
Abstract:The polysaccharide,adenosine and mannitol components of Cordycepstaii collected from the wild were determined, and the effects of aqueous C. taiiextracts on immune functions in mice were investigated using carbon clearance anddelayed type hypersensitivity testing(DTH),and by determining thymic and splenicindices. Polysaccharide, adenosine and mannitol levels in C. taii were 36.20 mg/g,
0.27 mg/g and 80.20 mg/g, respectively.Aqueous C. taii extracts partially alleviatedthe suppressive effects on the thymic and splenic indices caused bycyclophosphamide, and increased nonspecific immunity and cellular immunefunctions.Toxicity tests revealed that the LD50 for aqueous C. taii extract on oraladministration was69.42 g/kg.
Key words:Cordyceps taii;polysaccharide;adenosine;mannitol;carbonclearance;cellular immune function
Cordyceps sinensis (Berk.) Sacc. is a rare medicinal fungus in China withnumerous special pharmacological effects favoured by consumers. However, C.sinensis yields are decreasing year by year and the price of this limited resource isnow very high due to over gathering.However, other species within the genusCordyceps have often been reported to have similar chemical composition andpharmacological effects1 and might, there fore, serve as efficient sub stitutes for C.sinensis.One such alternative species is C. taii Liang et Liu which was firstlydiscovered and reported in Guizhou Province in 1991 2 and has subsequently beenfound in Anhui, Henan, Hunan and Guangdong Provinces. Comparison of thechemical composition of C. sinensis and C. taii showed that both species had similaramino ac id,vitamin and microe lement components3 .The microelement and aminoacid composition ofC. taii mycelia have also been reported 4,5 ,and extracts ofC.taii mycelia have antiseptic 6 , immunoregulatory 6~9 and tumor cell growthinhibiting functions 10 . In order to provide a basis for utilizing C. taii as analternative forC. sinensis, we have compared the levels of various bioactivecomponents in these two species,and studied the effect of aqueous C. taii extracts onnon specific immune functions, thymic and splenic indices,and cellular immunity inmic e.
1 Materials and Methods
1.1 Materials
C. taii was supplied by Guangdong Jin Cordyceps Biological Development Co.Ltd,and C. s inens is wa s purchas ed from Guangzhou Tongrentang Drugstore.
从介绍看啊,新增的HostYun 俄罗斯机房采用的是双向CN2线路,其他的像香港和日本机房,均为国内直连线路,访问质量不错。HostYun商家通用九折优惠码:HostYun内存CPUSSD流量带宽价格(原价)购买地址1G1核10G300G/月200M28元/月购买链接1G1核10G500G/月200M38元/月购买链接1G1核20G900G/月200M68元/月购买链接2G1核30G1500G/月...
HostKvm商家我们也不用多介绍,这个服务商来自国内某商家,旗下也有多个品牌的,每次看到推送信息都是几个服务商品牌一起推送的。当然商家还是比较稳定的,商家品牌比较多,这也是国内商家一贯的做法,这样广撒网。这次看到黑五优惠活动发布了,针对其主打的香港云服务器提供终身6折的优惠,其余机房服务器依然是8折,另还有充值50美元赠送5美元的优惠活动,有需要的可以看看。HostKvm是一个创建于2013年的...
wordpress外贸集团企业主题,wordpress通用跨屏外贸企业响应式布局设计,内置更完善的外贸企业网站优化推广功能,完善的企业产品营销展示 + 高效后台自定义设置。wordpress高级推广外贸主题,采用标准的HTML5+CSS3语言开发,兼容当下的各种主流浏览器,根据用户行为以及设备环境(系统平台、屏幕尺寸、屏幕定向等)进行自适应显示; 完美实现一套主题程序支持全部终端设备,保证网站在各...