Bioactive Components of Cordyceps taii and Their Immune
Functions in Mice
Abstract:The polysaccharide,adenosine and mannitol components of Cordycepstaii collected from the wild were determined, and the effects of aqueous C. taiiextracts on immune functions in mice were investigated using carbon clearance anddelayed type hypersensitivity testing(DTH),and by determining thymic and splenicindices. Polysaccharide, adenosine and mannitol levels in C. taii were 36.20 mg/g,
0.27 mg/g and 80.20 mg/g, respectively.Aqueous C. taii extracts partially alleviatedthe suppressive effects on the thymic and splenic indices caused bycyclophosphamide, and increased nonspecific immunity and cellular immunefunctions.Toxicity tests revealed that the LD50 for aqueous C. taii extract on oraladministration was69.42 g/kg.
Key words:Cordyceps taii;polysaccharide;adenosine;mannitol;carbonclearance;cellular immune function
Cordyceps sinensis (Berk.) Sacc. is a rare medicinal fungus in China withnumerous special pharmacological effects favoured by consumers. However, C.sinensis yields are decreasing year by year and the price of this limited resource isnow very high due to over gathering.However, other species within the genusCordyceps have often been reported to have similar chemical composition andpharmacological effects1 and might, there fore, serve as efficient sub stitutes for C.sinensis.One such alternative species is C. taii Liang et Liu which was firstlydiscovered and reported in Guizhou Province in 1991 2 and has subsequently beenfound in Anhui, Henan, Hunan and Guangdong Provinces. Comparison of thechemical composition of C. sinensis and C. taii showed that both species had similaramino ac id,vitamin and microe lement components3 .The microelement and aminoacid composition ofC. taii mycelia have also been reported 4,5 ,and extracts ofC.taii mycelia have antiseptic 6 , immunoregulatory 6~9 and tumor cell growthinhibiting functions 10 . In order to provide a basis for utilizing C. taii as analternative forC. sinensis, we have compared the levels of various bioactivecomponents in these two species,and studied the effect of aqueous C. taii extracts onnon specific immune functions, thymic and splenic indices,and cellular immunity inmic e.
1 Materials and Methods
1.1 Materials
C. taii was supplied by Guangdong Jin Cordyceps Biological Development Co.Ltd,and C. s inens is wa s purchas ed from Guangzhou Tongrentang Drugstore.
感恩一年有你!免费领取2核4G套餐!2核4G轻量应用服务器2核 CPU 4GB内存 60G SSD云硬盘 6Mbps带宽领取地址:https://cloud.tencent.com/act/pro/lighthousethankyou活动规则活动时间2021年9月23日 ~ 2021年10月23日活动对象腾讯云官网已注册且完成实名认证的国内站用户(协作者与子用户账号除外),且符合以下活动条件:账号...
CloudCone 商家在以前的篇幅中也有多次介绍到,这个商家也蛮有意思的。以前一直只有洛杉矶MC机房,而且在功能上和Linode、DO、Vultr一样可以随时删除采用按时计费模式。但是,他们没有学到人家的精华部分,要这样的小时计费,一定要机房多才有优势,否则压根没有多大用途。这不最近CloudCone商家有点小变化,有新人洛杉矶优化线路,具体是什么优化的等会我测试看看线路。内存CPU硬盘流量价格...
spinservers美国圣何塞机房的独立服务器补货120台,默认接入10Gbps带宽,给你超高配置,这价格目前来看好像真的是无敌手,而且可以做到下单后30分钟内交货,都是预先部署好了的。每一台机器用户都可以在后台自行安装、重装、重启、关机操作,无需人工参与! 官方网站:https://www.spinservers.com 比特币、信用卡、PayPal、支付宝、webmoney、Payssi...