Bioactive Components of Cordyceps taii and Their Immune
Functions in Mice
Abstract:The polysaccharide,adenosine and mannitol components of Cordycepstaii collected from the wild were determined, and the effects of aqueous C. taiiextracts on immune functions in mice were investigated using carbon clearance anddelayed type hypersensitivity testing(DTH),and by determining thymic and splenicindices. Polysaccharide, adenosine and mannitol levels in C. taii were 36.20 mg/g,
0.27 mg/g and 80.20 mg/g, respectively.Aqueous C. taii extracts partially alleviatedthe suppressive effects on the thymic and splenic indices caused bycyclophosphamide, and increased nonspecific immunity and cellular immunefunctions.Toxicity tests revealed that the LD50 for aqueous C. taii extract on oraladministration was69.42 g/kg.
Key words:Cordyceps taii;polysaccharide;adenosine;mannitol;carbonclearance;cellular immune function
Cordyceps sinensis (Berk.) Sacc. is a rare medicinal fungus in China withnumerous special pharmacological effects favoured by consumers. However, C.sinensis yields are decreasing year by year and the price of this limited resource isnow very high due to over gathering.However, other species within the genusCordyceps have often been reported to have similar chemical composition andpharmacological effects1 and might, there fore, serve as efficient sub stitutes for C.sinensis.One such alternative species is C. taii Liang et Liu which was firstlydiscovered and reported in Guizhou Province in 1991 2 and has subsequently beenfound in Anhui, Henan, Hunan and Guangdong Provinces. Comparison of thechemical composition of C. sinensis and C. taii showed that both species had similaramino ac id,vitamin and microe lement components3 .The microelement and aminoacid composition ofC. taii mycelia have also been reported 4,5 ,and extracts ofC.taii mycelia have antiseptic 6 , immunoregulatory 6~9 and tumor cell growthinhibiting functions 10 . In order to provide a basis for utilizing C. taii as analternative forC. sinensis, we have compared the levels of various bioactivecomponents in these two species,and studied the effect of aqueous C. taii extracts onnon specific immune functions, thymic and splenic indices,and cellular immunity inmic e.
1 Materials and Methods
1.1 Materials
C. taii was supplied by Guangdong Jin Cordyceps Biological Development Co.Ltd,and C. s inens is wa s purchas ed from Guangzhou Tongrentang Drugstore.
妮妮云的知名度应该也不用多介绍了,妮妮云旗下的云产品提供商,相比起他家其他的产品,云产品还是非常良心的,经常出了一些优惠活动,前段时间的八折活动推出了很多优质产品,近期商家秒杀活动又上线了,秒杀产品比较全面,除了ECS和轻量云,还有一些免费空间、增值代购、云数据库等,如果你是刚入行安稳做站的朋友,可以先入手一个119/元季付的ECS来起步,非常稳定。官网地址:www.niniyun.com活动专区...
Hostodo是一家成立于2014年的国外VPS主机商,现在主要提供基于KVM架构的VPS主机,美国三个地区机房:拉斯维加斯、迈阿密和斯波坎,采用NVMe或者SSD磁盘,支持支付宝、PayPal、加密货币等付款方式。商家最近对于上架不久的斯波坎机房SSD硬盘VPS主机提供66折优惠码,适用于1GB或者以上内存套餐年付,最低每年12美元起。下面列出几款套餐配置信息。CPU:1core内存:256MB...
青果网络怎么样?青果网络隶属于泉州市青果网络科技有限公司,青果网络商家成立于2015年4月1日,拥有工信部颁发的全网IDC/ISP/IP-VPN资质,是国内为数不多具有IDC/ISP双资质的综合型云计算服务商。青果网络是APNIC和CNNIC地址分配联盟成员,泉州市互联网协会会员单位,信誉非常有保障。目前,青果网络商家正式开启了618云特惠活动,针对国内外机房都有相应的优惠。点击进入:青果网络官方...