cellularBioactive Components of Cordyceps taii and Their Immune Functions in Mice

disable_functions  时间:2021-03-22  阅读:()

Bioactive Components of Cordyceps taii and Their Immune

Functions in Mice

Abstract:The polysaccharide,adenosine and mannitol components of Cordycepstaii collected from the wild were determined, and the effects of aqueous C. taiiextracts on immune functions in mice were investigated using carbon clearance anddelayed type hypersensitivity testing(DTH),and by determining thymic and splenicindices. Polysaccharide, adenosine and mannitol levels in C. taii were 36.20 mg/g,

0.27 mg/g and 80.20 mg/g, respectively.Aqueous C. taii extracts partially alleviatedthe suppressive effects on the thymic and splenic indices caused bycyclophosphamide, and increased nonspecific immunity and cellular immunefunctions.Toxicity tests revealed that the LD50 for aqueous C. taii extract on oraladministration was69.42 g/kg.

Key words:Cordyceps taii;polysaccharide;adenosine;mannitol;carbonclearance;cellular immune function

Cordyceps sinensis (Berk.) Sacc. is a rare medicinal fungus in China withnumerous special pharmacological effects favoured by consumers. However, C.sinensis yields are decreasing year by year and the price of this limited resource isnow very high due to over gathering.However, other species within the genusCordyceps have often been reported to have similar chemical composition andpharmacological effects1 and might, there fore, serve as efficient sub stitutes for C.sinensis.One such alternative species is C. taii Liang et Liu which was firstlydiscovered and reported in Guizhou Province in 1991 2 and has subsequently beenfound in Anhui, Henan, Hunan and Guangdong Provinces. Comparison of thechemical composition of C. sinensis and C. taii showed that both species had similaramino ac id,vitamin and microe lement components3 .The microelement and aminoacid composition ofC. taii mycelia have also been reported 4,5 ,and extracts ofC.taii mycelia have antiseptic 6 , immunoregulatory 6~9 and tumor cell growthinhibiting functions 10 . In order to provide a basis for utilizing C. taii as analternative forC. sinensis, we have compared the levels of various bioactivecomponents in these two species,and studied the effect of aqueous C. taii extracts onnon specific immune functions, thymic and splenic indices,and cellular immunity inmic e.

1 Materials and Methods

1.1 Materials

C. taii was supplied by Guangdong Jin Cordyceps Biological Development Co.Ltd,and C. s inens is wa s purchas ed from Guangzhou Tongrentang Drugstore.

CloudCone(20美元/年)大硬盘VPS云服务器,KVM虚拟架构,1核心1G内存1Gbps带宽

近日CloudCone商家对旗下的大硬盘VPS云服务器进行了少量库存补货,也是悄悄推送了一批便宜VPS云服务器产品,此前较受欢迎的特价20美元/年、1核心1G内存1Gbps带宽的VPS云服务器也有少量库存,有需要美国便宜大硬盘VPS云服务器的朋友可以关注一下。CloudCone怎么样?CloudCone服务器好不好?CloudCone值不值得购买?CloudCone是一家成立于2017年的美国服务...

wordpress简洁英文主题 wordpress简洁通用型高级外贸主题

wordpress简洁英文主题,wordpress简洁通用大气的网站风格设计 + 更适于欧美国外用户操作体验,完善的外贸企业建站功能模块 + 更好的移动设备特色模块支持,更高效实用的后台自定义设置 + 标准高效的代码程序功能结构,更利于Goolge等国际搜索引擎的SEO搜索优化和站点收录排名。点击进入:wordpress简洁通用型高级外贸主题主题价格:¥3980 特 惠 价:¥1280安装环境:运...

快快云:香港沙田CN2/美国Cera大宽带/日本CN2,三网直连CN2 GIA云服务器和独立服务器

快快云怎么样?快快云是一家成立于2021年的主机服务商,致力于为用户提供高性价比稳定快速的主机托管服务,快快云目前提供有香港云服务器、美国云服务器、日本云服务器、香港独立服务器、美国独立服务器,日本独立服务器。快快云专注为个人开发者用户,中小型,大型企业用户提供一站式核心网络云端服务部署,促使用户云端部署化简为零,轻松快捷运用云计算!多年云计算领域服务经验,遍布亚太地区的海量节点为业务推进提供强大...

disable_functions为你推荐
诊断snsinternalservererrorHTTP/1.1500Internal Server Error.怎么办呐access数据库修复Access数据库恢复,有些表被损坏或有些表的部分记录被损坏,求解啊asp.net网页制作如何用ASP.NET做网站?银花珠树晓来看谜语白色花无人栽一夜北风遍地开。旡根无叶又无枝不知是谁送花来。谜底是什么小型汽车网上自主编号申请机动车自主选号有几种办法徐州商标介绍徐州的一种产品泉州商标注册泉州本地商标注册要怎么注册?具体流程是什么?瑞东集团中粮集团是什么性质的企业可信网站可信网站认证怎么做?贵不?价格大概是多少?
域名主机空间 vps优惠码 免费注册网站域名 locvps 68.168.16.150 info域名 创宇云 NetSpeeder 一点优惠网 hnyd 免费全能空间 共享主机 空间技术网 东莞服务器 吉林铁通 789 免费ftp 防cc攻击 域名转入 重庆服务器 更多