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ElabscienceVPS45PolyclonalAntibodyCatalogNo.
E-AB-17268ReactivityH,M,RStorageStoreat-20℃.
Avoidfreeze/thawcycles.
HostRabbitApplicationsIHC,ELISAIsotypeIgGNote:Centrifugebeforeopeningtoensurecompleterecoveryofvialcontents.
ImagesImmunohistochemistryofparaffin-embeddedHumanlivercancertissueusingVPS45PolyclonalAntibodyatdilution1:50ImmunogenInformationImmunogenFusionproteinofhumanVPS45GeneAccessionBC012932SwissprotQ9NRW7SynonymsPP2A,PPP2R4,PR53,PTPA,Serine/threonine-proteinphosphatase2AregulatorysubunitB'ProductInformationBufferPBSwith0.
05%sodiumazideand50%glycerol,PH7.
4PurifyAffinitypurificationDilutionIHC1:30-150,ELISA1:2000-10000BackgroundVesiclemediatedproteinsortingplaysanimportantroleinsegregationofintracellularmoleculesintodistinctorganelles.
Geneticstudiesinyeasthaveidentifiedmorethan40vacuolarproteinsorting(VPS)genesinvolvedinvesicletransporttovacuoles.
ThisgeneisamemberoftheSec1domainfamily,andshowsahighdegreeofsequencesimilaritytomouse,ratandyeastVps45.
Theexactfunctionofthisgeneisnotknown,butitshighexpressioninperipheralbloodmononuclearcellssuggestsaroleintraffickingproteins,includinginflammatorymediators.
Multiplealternativelysplicedtranscriptvariantshavebeenfoundforthisgene.
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Applications:WB-WesternBlotIHC-ImmunohistochemistryIF-ImmunofluorescenceIP-ImmunoprecipitationFC-FlowcytometryChIP-ChromatinImmunoprecipitationReactivity:H-HumanR-RatM-MouseMk-MonkeyDg-DogCh-ChickenHm-HamsterRb-RabbitSh-SheepPg-PigZ-ZebrafishX-Xenopus